Peyronie’s disease is a condition that causes painful, curved erections that are not cancerous. It is caused by fibrous scar tissue that forms on the penis. Penises vary in shape and size, and having a nonsignificant erection isn’t always a sign of trouble. Peyronie’s disease causes a significant bend or pain in some men, once the penis is fully erect

This could make it impossible for you to have sex or hard for you to get or keep an erection (erectile dysfunction). Peyronie’s disease causes stress and anxiety in many men. Penile shortening is another common concern.

Peyronie’s disease does not usually go away on its own. Most men with Peyronie’s disease will see their condition worsen or remain the same. If the condition is treated soon after it starts, it might not get worse or the symptoms might even get better. Even if you’ve had the condition for a while, treatment may help alleviate annoying symptoms like pain, curvature, and penile shortening.

Depressed due to Peyronie's Disease

How and Why Plaques grows Around The Penis

Most people with Peyronie’s disease get plaques on the top (or dorsal) side of their penis. Plaques cause the tunica albuginea to become less flexible, which could lead to the penis bending upward as it stiffens. The bend will be downward or sideways when plaques develop on the bottom or side of the penis. Multiple plaques are present in certain individuals, which may result in complex curves.

There are times when plaques grow all the way around the penis. The shaft of the penis may narrow, much like the neck of a bottle, even though these plaques most frequently do not induce curvature. Sometimes, this is referred to as “bottlenecking,” “bottle-necking,” or “waisting.” In very bad cases, the plaque can build up calcium and get so hard that it looks like a bone. Men might also discover that their penis has gotten smaller or shorter.

The curvature of the penis observed in Peyronie’s disease, is a disorder where the penis bends abnormally when erect. It is a very uncommon cause of erectile dysfunction, a condition where men have trouble getting or keeping an erection. The penis has three tubes that look like sponges. Together, they are called the corpora cavernosa and the urethra. The penis’ function is to expel urine through the urethra and ejaculate sperm.

The erectile tissue of the penis is called the corpus cavernosal. When a male gets sexually aroused, the blood vessels in these tubes fill with blood, causing an erection. The penile smooth muscle’s relaxation and contraction are controlled by calcium in the cells. When fibrous scar tissue forms beneath the skin of the penis, Peyronie’s disease happens, causing the penis to curve awkwardly when it is erect.

The National Institute of Health thinks that 1 in 100 people have Peyronie’s disease. During the healing process, cells can get stuck where the injury was, which can lead to scar tissue. During the healing process, cells can get stuck at the site of the injury, making scar tissue.

The tunica albuginea, an elastic tissue shell, surrounds the corpora cavernosa. When the penis is erect, this sheath stretches. The tissue of this elastic coating may deteriorate if a person injures their penis. Correct healing won’t have any observable effects.

Peyronies Diseases In Panis

But there is a chance that someone with persistent scar tissue could get Peyronie’s disease. When the penis is erect, the scarred area of the shell that cannot stretch pulls on the penis, bending it because it can no longer stretch as it should.

However, Peyronie’s disease does not always manifest in males who sustain penile injuries. Some people may be more predisposed to it than others due to certain risk factors.

Risk Elements Associated with Peyronie’s disease

The following are some potential Peyronie’s disease risk factors:

  • Penile damage
  • Diabetes
  • Family history of connective tissue diseases
  • Regular alcohol Consumption
  • Hypogonadism
  • Smoking
  • Age

Peyronie’s disease may occasionally be inherited since those who have close relatives who have it are more likely to get it themselves.

Peyronie’s illness also has a connection to Dupuytren’s contracture, a condition of the connective tissue. Because of this condition, the tissues in the hand get thicker and tighter, pulling the fingers in.

Peyronie’s disease is likely caused in some cases by a problem with the immune system since it can sometimes show up without causing any harm.

Symptoms Of Peyronie’s disease

Peyronie’s disease signs and symptoms may appear gradually or suddenly. lumps in the penis that are twisted or curved and painful erections

Tender erections having sex problems as a result of a crooked or bent penis Over 75% of Peyronie’s disease patients are agitated or depressed as a result of it. Unfortunately, a lot of Peyronie’s disease sufferers decide to remain silent out of embarrassment.

How Common is Peyronie’s illness?

It is estimated that 4 out of 100 males between the ages of 40 and 70 will get Peyronie’s disease. Men in their 30s have reported having it, although it is uncommon in young men. Many men may not go to the doctor because they don’t want to be embarrassed. Because of this, the actual number of cases may be higher than expected.

It’s interesting to notice that the number of Peyronie’s disease cases has increased recently. This could happen if new medications for erectile dysfunction (ED) hit the market and doctors found Peyronie’s disease in men who went to them for ED treatment. This may lead to an increase in the reported instances of Peyronie’s disease.

Stages of Peyronie’s disease 

Two stages of Peyronie’s disease exist:


6–18 months are spent in the acute phase.

dependable source Pain and a significant curvature of the penis are the main symptoms. When the scar tissue is still forming, a person may experience pain.

Under the skin of the penis, there is scar tissue that can be felt. It has a tough tissue-texture belt. It could resemble flattened lumps to some people. People often get erectile dysfunction (ED) all of a sudden or for the first time. This is a condition in which men have trouble getting or keeping an erection.

Depending on where the plaques are, the penis may bend laterally, downward, or upward. The erect penis can occasionally get incredibly small at a specific point. The bend becomes more pronounced in some people over time.

Others notice a steady improvement. The curve remains the same for others as well. The penis may gradually shorten as a result of Peyronie’s disease.


The scar tissue stops forming at the chronic stage. One of the signs could be ED.

Most of the time, people do not feel much discomfort during the chronic phase.

the plaque formation in Peyronie's Disease

Cause of Peyronie’s Disease

A slight penile injury is most likely the origin of Peyronie’s disease. (See erectile injury.) Although it can also be brought on by sports or other incidents, this kind of damage is most frequently brought on by strenuous intercourse (such as bending the penis during penetration or pressure from a partner’s pubic bone). The tunica albuginea may get injured, leading to the cellular formation of scar tissue (fibrosis). The plaque of Peyronie’s disease is then created by this scar tissue. A difficulty with the body’s ability to repair wounds is what causes Peyronie’s disease.


A urologist, a doctor who specializes in sexual and urinary health, will ask a person about their medical history, symptoms, and how long they have been happening (suddenly or over time). Additionally, their doctor will conduct a physical examination if necessary.

Plaques in the penis can be felt by a doctor even when it is not erect. If they need someone to have an erection in order to check for scar tissue, they could need to use medicine to induce one or ask the subject to pose for pictures in their own house.

Additionally, the doctor might decide to use a dynamic ultrasound. This kind of ultrasonography makes use of sound waves to map out the plaque, check for calcium buildup, and assess blood flow within the penis.


The doctor will likely advise waiting it out if the patient’s curvature is not deteriorating, there is little to no pain, and the symptoms do not interfere with sex or urine.

Before deciding to do surgery, a doctor will usually wait at least a year to see if things get better.

During the active phase, less invasive treatments are often recommended, while more invasive treatments are usually given during the chronic phase.

Males with Peyronie’s disease do not necessarily need to be treated. The end goal is to make a man feel less uncomfortable so he can have sex again. The course of treatment is typically somewhat conservative.

alterations in way of life

Peyronie’s disease has no known treatment. However, certain lifestyle adjustments might lessen the severity of symptoms. These consist of:

  • Reducing alcohol consumption
  • Giving up smoking
  • Eliminating illicit drugs
  • Working out frequently
  • Nonsurgical Procedures

Using the following, some Peyronie’s disease patients have seen relief:

# Shock wave treatment: Scar tissue is broken up by this therapy.

# Vacuum equipment for enlargement: Straightning or traction therapy for the penis to reduce or remove the curvature. These may aid in extending the penis.

# Penile shots. Some doctors may decide to give an injection of interferon to help break down fibrous tissue and slow its growth.

Food and Drug Administration ( US FDA) has only approved the injection drug collagenase (Clostridium hystolyticum) to treat Peyronie’s disease (Xiaflex). Doctors use this penile injection on patients whose penis bends at an angle of 30 degrees or more when erect. It is an enzyme that shrinks plaques and occasionally completely eradicates them.

Curvature of the Peyronie's Disease

surgical procedures

If the curvature is severe and makes it hard for the patient to have sexual relations, the urologist may suggest surgery. Most doctors agree that a patient must have been pain-free for a certain amount of time before surgery can be considered. Additionally, the curvature must have ceased advancing.

These consist of:

The penis on one side is shrinking. The unaffected side of the penis, or the side without plaques, may be cut shorter. This prevents bending when having an erection. The penis is made shorter with this operation. So, doctors will usually consider this treatment if the curvature is not too bad (so less shortening is needed) and the man’s penis is long enough.

lengthening the penis on one side. The surgeon cuts away the scar tissue, which lets the sheath grow again. Males’ erect penises will be straight if the sheath extends far enough. The surgeon may remove some scar tissue during the treatment and graft new tissue over the areas that were removed. Patients who have a shorter penis or a more severe bend in it benefit the most from this operation. However, extending the side is more likely to cause impotence than shortening it.

Implants can be surgically put into the soft tissue that swells up with blood when a man is sexually aroused and causes an erection. There are two types of implants: those that are permanent and those that activate a scrotal pump to inflate. Permanent implants will build up a male penis that is semi-rigid and good for sexual activity. The pump-activated one will also deliver a better erection concurrently. To lessen curvature, the surgeon can cut away portions of the scar tissue.

Medication For Peyronie’s disease 

potassium aminobenzoate with vitamin E. While these drugs may lessen pain, they often have little to no effect on an aberrant curvature that already exists.

PDE5 blockers. Doctors frequently recommend ED drugs like tadalafil (Cialis, Adcirca). Even though these drugs are meant to treat ED, they might also be able to improve Peyronie’s symptoms, particularly during the acute stage.

Some problems with Peyronie’s disease include not being able to have sexual activity because of pain, erectile dysfunction (ED), or both.

The patient may also have a lot of worry, stress, or depression, which could make their erectile dysfunction worse. Relationship problems and challenges in fathering a child may be brought on by Erectile Dysfunction.

Anyone who is feeling pain or discomfort because of a curved penis should see a doctor. There are various treatment possibilities.

Prevention Of Peyronie’s Disease

Peyronie’s disease can’t be stopped because each person’s body reacts differently to damage and inflammation.

The way the penis feels, works, or looks can change at any time, and anyone who notices these changes should talk to their doctor.

Male Prespective

A man’s penis typically has a small curvature. But the bend is a problem if it hurts, makes you have urinary or sexual problems, or is too extreme.

Peyronie’s disease can cause ED, which can make it hard for men to have sexual relations. For a good diagnosis and course of therapy, a patient should visit their doctor.

Stress and anxiety can also be brought on by worrying over the curve of a person’s penis. Many adult men with Peyronie’s disease who have satisfying sex lives have a good outlook.

Some Commonly Asked Questions

Here are some further Peyronie’s disease-related queries and their respective responses.

Peyronie’s disease: an STD or not?

Since it is not an STI, Peyronie’s illness cannot spread from one person to another.

Does Peyronie’s illness have a natural cure?

Peyronie’s illness very rarely disappears on its own. Early detection and treatment are ideal because the illness may get worse with time.

What might be confused with Peyronie’s disease?

A medical professional may occasionally identify corporal fibrosis. This is the scarring that develops within the tissue of the erectile organ. The disorders Peyronie’s disease, priapism, sickle cell anemia, and trauma to the penis are some of the potential reasons.

A doctor could give the wrong diagnosis to a patient if they thought that something other than Peyronie’s disease caused the scarring and the ED that went along with it.

Epithelioid sarcoma of the penis is a rare cancer of the penis that might be mistaken for Peyronie’s disease. This sarcoma is relatively easily curable.

When does a crooked penis becomes a serious problem?

Penile fracture though uncommon but is a very serious injury. and a painful event if it occurs due to whatever reason or accident. An emergency occurs when an erect penis is violently bent. Surgery is necessary for treating such a condition.


This information is for educational purposes only, and no medical advice should be inferred from it. Before changing your diet or adding supplements, please talk to your doctor.

The author’s views are his or her own. The facts and opinions in the article have been taken from various articles and commentaries available in the online media and Eastside Writers does not take any responsibility or obligation for them.

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